27/05/19

Haematological and biochemical parameters of weaned piglets fed on fodder mixture contaminated by Zearalenone with the addition of clinoptilolite

Summary

The aim of this study was to evaluate the effect of zeolite (clinoptilolite - CLIN) on some
metabolic parameters in blood serum and haematological
values in weaned piglets fed with increased levels of
zearalenone (ZEN) was investigated over a 14-day period.
  • Animals
  • The research involved four
    groups of weaned piglets
    aged 40 to 54 days. All
    groups were fed on fodder
    mixture for growing pigs
    containing 20% crude protein
    and 12.57 MJ ME/kg.

    • The first control group (C1) received a concentrate
      mixture without addition
      of ZEN or mycotoxin
      adsorbent MINAZEL PLUS®.
    • The second control
      group (C2)
      was fed on
      fodder mixture containing
      0.2% of modified zeolite(MINAZEL PLUS®; levels of
      zearalenone <5.1 ng/g).<5,1 ng/g).
    • Piglets in thefirst
      experimental group
      (E1)
      were fed on fodder
      mixture containing added
      zearalenone (3 mg/
      kg) (Sigma-Aldrich Co) and
      0.2% of MINAZEL PLUS® preparation.
    • The second experimental
      group (E2)
      was fed on
      fodder mixture to which 3
      mg/kg of zearalenone was
      added, but with no addition
      of MINAZEL PLUS®.

    Results

    Oestrogenic effect of ZEN and Insulin resulted in synergistic
    action which was demonstrated by an increased total protein
    level, lower level of glucose, triacylglycerols, serum iron, a higher
    level of cholesterol and higher amino transaminase activity.

Conclusions

The metabolic anti oestrogen effect of ZEN was established
in group E2, whereas group E1 manifested the agonistic
effect due to oestrogen reduction by modified zeolite.

Authors


Šperanda Marcela1, Liker B.2, Šperanda T.1, Šerić V.3, Antunović Z1, Grabarević Ž.4, Senčić D.1, Grgurić D.5 y Steiner Z.1

1Faculty of Agriculture, Osijek, Croatia;
2Faculty of Agriculture, Zagreb (Croatia);
3 Clinical Hospital Osijek (Croatia);
4Faculty of Veterinary Medicine, Zagreb (Croatia) and
5Centar for Livestock Improvement, Osijek

Micotoxicosis prevention
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