03/04/19

Comparative investigation of the efficacy of three different adsorbents against OTA-Induced toxicity in broiler chickens

Summary

The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic
components, with the addition of enzymes), in protecting
broilers from the toxic effects of Ochratoxin A in feed.
  • Animals
  • Broilers were fed diets
    containing 2 mg/kg
    of Ochratoxin A (OTA)
    and supplemented
    with adsorbents at the
    recommended concentration
    of 2 g/kg for 21 days.

    The presence of OTA led to a notable reduction in body
    weight, lower weight gain, increased feed conversion and
    induced histopathological changes in the liver and kidneys.
    The presence of inorganic, organic and mixed adsorbents
    in contaminated feed only partially reduced the negative
    effects of OTA on the broiler performances:

      Body weight: broilers that were fed with adsorbent-supplemented
      feed reached higher body weight in
      comparison to the group that only received OTA.

    • +17,96% with the treatment with the inorganic adsorbent
    • +19,09% with the treatment with the organic adsorbent
    • +13,59% with the mixed adsorbents
      Feed consumption: the presence of adsorbents partially
      alleviated the reduction in feed consumption.

    • +22,68% with the treatment with the inorganic adsorbent
    • +12,91% with the treatment with the organic adsorbent
    • +10,59% with the mixed adsorbents
      Feed conversion: a similar effect was observed with feed conversion.
      The applied adsorbents have also reduced the intensity
      of histopathological changes caused by OTA; however,
      they were not able to prevent their onset.

After the withdrawal of the
toxin and adsorbents from
the feed (21–42 days), all
previously observed disturbances
in broilers were reduced, but
more remarkably in broilers
fed with adsorbents.
Authors


Jelena Nedeljković-Trailović1, Saša Trailović1, Radmila Resanović1, Dragan Milićević2, Milijan Jovanovic1, and Marko Vasiljevic3
1Faculty of Veterinary Medicine, University of Belgrade, Belgrade (Serbia)
2Institute of Tecnology and Hygiene , Belgrade (Serbia)
3 PATENT CO. Mišićevo (Serbia)
Micotoxicosis prevention
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