Comparative investigation of the efficacy of three different adsorbents against OTA-Induced toxicity in broiler chickens

Summary
The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of Ochratoxin A in feed.
  • Animals
  • Broilers were fed diets containing 2 mg/kg of Ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days.
    The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances:
      Body weight: broilers that were fed with adsorbent-supplemented feed reached higher body weight in comparison to the group that only received OTA.
    • +17,96% with the treatment with the inorganic adsorbent
    • +19,09% with the treatment with the organic adsorbent
    • +13,59% with the mixed adsorbents
      Feed consumption: the presence of adsorbents partially alleviated the reduction in feed consumption.
    • +22,68% with the treatment with the inorganic adsorbent
    • +12,91% with the treatment with the organic adsorbent
    • +10,59% with the mixed adsorbents
      Feed conversion: a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset.
After the withdrawal of the toxin and adsorbents from the feed (21–42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.
Authors
Jelena Nedeljković-Trailović1, Saša Trailović1, Radmila Resanović1, Dragan Milićević2, Milijan Jovanovic1, and Marko Vasiljevic3
1Faculty of Veterinary Medicine, University of Belgrade, Belgrade (Serbia) 2Institute of Tecnology and Hygiene , Belgrade (Serbia) 3 PATENT CO. Mišićevo (Serbia)


Micotoxicosis prevention
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