Effectiveness of a novel multicomponent mycotoxin detoxification agent in the presence of AFB1 and T-2 toxin in broiler chicks


OBJECTIVE  

This experimental study was conducted to determine the ability of a novel mycotoxin detoxification agent (MycoRaid) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T‑2 toxin, alone or in combination, and to examine its effect on:

  • Performance
  • Pathohistological changes
  • Presence of residues of these toxins in the tissues of broiler chicks


MATERIALS & METHODS  

A total of 96 broiler chicks were divided into eight equal groups:

Group C: this group served as a control (without any additives).

Group MR: this group received the novel detoxification agent, MycoRaid (MR) at a concentration of 0.2%.

Group E-I: this group received a diet containing 0.1 mg AFB1/kg of feed.

Group E-II: this group received a diet containing 0.1 mg AFB1/kg of feed + MR 0.2%.

Group E-III: this group received a diet containing 0.5 mg T‑2 toxin/kg of feed.

Group E-IV: this group received a diet containing 0.5 mg T‑2 toxin/kg of feed + 0.2% MR.

Group E-V: this group received a diet with a combination of 0.1 mg AFB1/kg of feed and 0.5 mg T‑2 toxin/kg of feed.

Group E-VI: this group received a diet with a combination of 0.1 mg AFB1/kg of feed and 0.5 mg T‑2 toxin of feed + 0.2% MR.


RESULTS  

Results indicate that feed containing AFB1 and T‑2 toxin, alone or in combination, adversely affected poultry health and performance.

However, the addition of MR to diets containing AFB1 and T‑2 toxin, alone and in combination, exerted a positive effect on:

  • Body weight
  • Feed intake
    Weight gain
  • Feed efficiency
  • Microscopic lesions in visceral organs
Additionally, residual concentrations of AFB1 in liver samples were significantly decreased (p < 0.05) when chicks were fed diets supplemented with 0.2% of MR.

Authors

Darko Stefanović1, Darko Marinković1, Saša Trailović1, Marko Vasiljević2, Hunor Farkaš2, Jog Raj2, Nataša Tolimir3, Stamen Radulović1, Vladimir Nešić1, Jelena Nedeljković Trailović1, and Branko Petrujkić1
1Faculty of Veterinary Medicine, University of Belgrade, Serbia
2Patent Co., DOO, Vlade Ćetkovića, Mišićevo, Serbia.
3Institute for Science Application in Agriculture, Belgrade, Serbia.

Stefanović, D.; Marinković, D.; Trailović, S.; Vasiljević, M.; Farkaš, H.; Raj, J.; Tolimir, N.; Radulović, S.; Nešić, V.; Trailović, J.N.; et al. Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T‑2 T

Micotoxicosis prevention
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